Gluco-Support Formula™
Support for healthy glucose metabolism
DESCRIPTION
Gluco-Support Formula™ provided by Douglas Laboratories is a synergistic and comprehensive combination of vitamins, minerals, herbals, and other nutrients carefully formulated and specifically designed to offer nutritional support for healthy glucose metabolism.
FUNCTIONS
Studies show that a high percentage of adults in North America and other developed countries eat less than the minimum daily allowance of 10 or more essential nutrients. Adequate amounts and proper balance of these nutrients are needed not only for maintaining good health, but also for the dietary management of the body’s structure as well as the optimum functioning of its various systems, including the immune system. The Gluco-Support Formula™ has been carefully developed to contain the right proportions of vitamins, minerals, trace elements, and other nutrients without danger of toxic build-up or other side effects. Each ingredient is selected in consideration of its absorbability, competitive relationship with other nutrients, allergenic potential, and long-term safety. Certain nutrients such as beta-carotene, vitamin C, vitamin E and B-complex vitamins are included in high-potency amounts because of the vital roles they play in antioxidant protection, energy production, the maintenance of healthy blood cells, the nervous system, hormonal balance, and more. Minerals and trace elements are provided in their safest and most bioavailable forms.
Gluco-Support Formula™ contains not only the base formula of Douglas Laboratories' Ultra-Specific Nutrition 2000 Series™ that offers intensive support for the healthy functioning of the body in general, but also a blend of herbs and additional nutrients specifically formulated to offer additional support of the body’s mechanisms that maintain healthy glucose metabolism.
Glucose metabolism that is associated with abnormally high blood glucose can lead to high levels of glycation. Glycation is the non-enzymatic attachment of sugars to major molecules in the body, including proteins, lipids, and nucleic acids. Glycation reactions generate advanced glycation end-products (AGEs) and glycotoxin intermediates. AGEs cause abnormal and destructive functioning of body proteins, lipids, and nucleic acids. AGE-associated damage is suspected in the pathogenesis of many diseases and age-related deteriorations.
There are three primary routes by which nutritional components can help prevent AGE formation. Maintenance of normal blood glucose levels is fundamental to preventing AGE formation. Chromium is an integral component of the glucose tolerance factor (GTF), a naturally occurring compound of chromium, nicotinic acid, and amino acids that is essential for proper glucose metabolism. Adequate chromium nutrition is essential for the formation of GTF and subsequent control of blood glucose levels.
Gymnema sylvestre is an Ayurvedic botanical that may assist in the normal regeneration and repair of healthy pancreatic beta cells. Gymnema is also suspected of reducing intestinal glucose absorption. Biotin serves as a cofactor of glucose metabolism and induces glucokinase, an enzyme that encourages cells to retain glucose for energy production rather than release it into the blood stream. Alpha-lipoic acid appears to enhance glucose use by muscles by augmenting muscle protein content.
INDICATIONS
Gluco-Support Formula™ tablets may be a useful dietary supplement for those who wish to nutritionally support their healthy glucose metabolism.
FORMULA (#84075)
Four Tablets Contain:
500 mg Gluco-Support Proprietary Blend of:
Momordica, Gymnema Extract, Chickweed, Dandelion, Goldenseal, Acetyl-L-Carnitine, Lemon Bioflavonoids, Proanthcyanidins (Red Wine Grape), Lipoic Acid andCoenzyme Q-10
Vitamin A (Palmitate).................................. 5,000.. I.U.
Beta-carotene............................................. 15,000.. I.U.
Vitamin C (Ascorbic Acid).......................... 1,000.. mg
Vitamin D-3......................................................... 50.. I.U.
Vitamin E (as Vitamin E Succinate)............. 200.. I.U.
Thiamin (as Thiamin HCl)............................... 50.. mg
Riboflavin............................................................ 25.. mg
Niacin/Niacinamide......................................... 120.. mg
Vitamin B-6......................................................... 25.. mg
(as Pyridoxine HCl/
Pyridoxal-5-Phosphate Complex)
Folic Acid........................................................... 800.. mcg
Vitamin B-12 (on Ion Exchange Resin)...... 100.. mcg
Biotin.................................................................. 300.. mcg
Pantothenic Acid.............................................. 150.. mg
(as d-Calcium Pantothenate)
Calcium............................................................. 300.. mg
(from Calcium Citrate/Ascorbate Complex)
Magnesium....................................................... 300.. mg
(from Magnesium Aspartate/Ascorbate Complex)
Zinc (from Zinc Aspartate Complex)............. 20.. mg
Selenium............................................................ 200.. mcg
(Organic Selenium from Krebs† Cycle and Kelp)
Copper (from Copper Amino Acid Chelate)... 2.. mg
Manganese.......................................................... 15.. mg
(from Manganese Aspartate Complex)
Chromium......................................................... 200.. mcg
(Organically bound with GTF activity
-low allergenicity)
Molybdenum (from Molybdenum Krebs†)... 50.. mcg
Potassium............................................................ 75.. mg
(from Potassum Aspartate Complex)
Choline (from Choline Citrate/Bitartrate)..... 20.. mg
Inositol................................................................. 25.. mg
Citrus Bioflavonoid Complex....................... 100.. mg
PABA (Para-Aminobenzoic Acid)................... 50.. mg
Vanadium (from Vanadium Krebs†).............. 25.. mcg
Boron...................................................................... 1.. mg
(from Boron Aspartate/Citrate Complex)
Trace Elements (from Sea Vegetation)........ 100.. mcg
†Krebs=Citrate, Fumarate, Malate, Glutarate and Succinate Complex
SUGGESTED USE
Adults take 4 tablets daily with meals or as directed by physician.
SIDE EFFECTS
No adverse effects have been reported.
STORAGE
Store in a cool, dry place, away from direct light. Keep out of reach of children.
REFERENCES
Ahmad, N, Hassan, MR, Halder, H, Bennoor, KS. Effect of Momordica charantia (Karolla) extracts on fasting and postprandial serum glucose levels in NIDDM patients. Bangladesh Med Res Counc Bull 1999;25:11-3.
Anderson, RA. Nutritional factors influencing the glucose/insulin system: chromium. J Am Coll Nutr 1997;16:404-10.
Bierhaus, A, Chevion, S, Chevion, M, Hofmann, M, Quehenberger, P, Illmer, T, Luther, T, Berentshtein, E, Tritschler, H, Muller, M, Wahl, P, Ziegler, R, Nawroth, PP. Advanced glycation end product-induced activation of NF-kappaB is suppressed by alpha-lipoic acid in cultured endothelial cells. Diabetes 1997;46:1481-90.
Cunningham, JJ. Micronutrients as nutriceutical interventions in diabetes mellitus. J Am Coll Nutr 1998;17:7-10.
Jacob, S, Ruus, P, Hermann, R, Tritschler, HJ, Maerker, E, Renn, W, Augustin, HJ, Dietze, GJ, Rett, K. Oral administration of RAC-alpha-lipoic acid modulates insulin sensitivity in patients with type-2 diabetes mellitus: a placebo- controlled pilot trial. Free Radic Biol Med 1999;27:309-14.
Kaneto, H, Fujii, J, Myint, T, Miyazawa, N, Islam, KN, Kawasaki, Y, Suzuki, K, Nakamura, M, Tatsumi, H, Yamasaki, Y, Taniguchi, N. Reducing sugars trigger oxidative modification and apoptosis in pancreatic beta-cells by provoking oxidative stress through the glycation reaction. Biochem J 1996;320:855-63.
Levi, B, Werman, MJ. Long-term fructose consumption accelerates glycation and several age- related variables in male rats. J Nutr 1998;128:1442-9.
Raza, H, Ahmed, I, John, A, Sharma, AK. Modulation of xenobiotic metabolism and oxidative stress in chronic streptozotocin-induced diabetic rats fed with Momordica charantia fruit extract. J Biochem Mol Toxicol 2000;14:131-9.
Shimizu, K, Ozeki, M, Tanaka, K, Itoh, K, Nakajyo, S, Urakawa, N, Atsuchi, M. Suppression of glucose absorption by extracts from the leaves of Gymnema inodorum. J Vet Med Sci 1997;59:753-7.
Yaworsky, K, Somwar, R, Ramlal, T, Tritschler, HJ, Klip, A. Engagement of the insulin-sensitive pathway in the stimulation of glucose transport by alpha-lipoic acid in 3T3-L1 adipocytes [In Process Citation]. Diabetologia 2000;43:294-303.